4.4 Article

Sensing cyanide ion via fluorescent change and its application to the microfluidic system

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 26, Pages 4102-4105

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.04.139

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Funding

  1. National Research Foundation of Korea [R11-2005-008-02003-0, R11-2005-008-05001-0, R0A-2007-000-20007-0] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We introduce a cyanide selective microfluidic platform, in which fluorescent chemodosimeter 1 displayed a selective green fluorescence upon the addition of cyanide. Our system was examined in aqueous solution, and the 'OFF-ON' type emission change can be monitored over 500 nm. In addition, colorimetric change was also observed upon the addition of cyanide. The practical use of the probe was demonstrated by its application to the detection of cyanide in the living cells. (C) 2008 Elsevier Ltd. All rights reserved.

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