4.4 Article

A chemoselective aerobic oxidation of benzylic azides catalyzed by molybdenum xanthate in an aqueous medium

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 29-30, Pages 4526-4530

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.05.047

Keywords

benzyl azides; molybdenum; redox reactions; aerobic oxidations; chemoselectivity; green chemistry

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A mild molybdenum-catalyzed, aerobic, chemoselective oxidation of benzylic azides to the corresponding aldehydes in an aqueous medium that tolerates a variety of functional groups including alcohols, esters, ketones, halides and olefins is described. (c) 2008 Elsevier Ltd. All rights reserved.

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