A mild preparation of substituted indolizines and indole from simple aromatic precursors using (trimethylsilyl)diazomethane

A mild and convenient synthesis of substituted indolizines from readily available 2-(pyridin-2-yl)acetyl derivatives using (trimethylsilyl)diazomethane is described. The extension of this methodology to the synthesis of indole from 2-aminobenzaldehyde is also reported. (c) 2008 Elsevier Ltd. All rights reserved.