4.4 Article

One-pot synthesis of β-hydroxysulfides from styrenes and disulfides using the Zn/AlCl3 system

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 47, Pages 6712-6714

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.09.071

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Funding

  1. K.N. Toosi University of Technology Research Council
  2. Iranian National Science Foundation [86063/21]

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A simple, general, and highly regioselective procedure has been developed for the one-pot synthesis of beta-hydroxysulfides in good yields from various styrenes and disulfides by cleavage of the S-S bond with a Zn/AlCl3 system in aqueous acetonitrile at 80 degrees C and in the presence of oxygen. (c) 2008 Elsevier Ltd. All rights reserved.

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