Journal
TETRAHEDRON LETTERS
Volume 49, Issue 18, Pages 2969-2973Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.03.001
Keywords
trans-beta-amino acid; AZT; oligonucleoside; NMR; helical turn
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Homo short-oligomers of a novel trans-beta-amino acid derived from AZT were synthesized and characterized. These adopt right-handed helical turns with their bases positioned systematically along the helix axis. These studies open up new possibilities for synthesizing nucleoside derived functional foldamers. (C) 2008 Elsevier Ltd. All rights reserved.
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