Journal
TETRAHEDRON LETTERS
Volume 49, Issue 17, Pages 2681-2684Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.02.164
Keywords
aldol reaction; aryl alkyl ketones; pyrrolidine sulfonamide
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A (S)-pyrrolidine sulfonamide catalyzed asymmetric direct aldol reaction of aryl methyl ketones with aromatic aldehydes has been developed with moderate to good enantioselectivities. The study considerably broadens the substrate scope of chiral amines promoted aldol processes. (c) 2008 Elsevier Ltd. All rights reserved.
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