4.4 Article

Effective synthesis of nucleosides with glycosyl trifluoroacetimidates as donors

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 34, Pages 5036-5038

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.06.042

Keywords

glycosyl trifluoroacetimidates; nucleosides; N-glycosylation

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Glycosyl trifluoroacetimidates have been disclosed to be effective glycosyl donors for the synthesis of nucleosides; the present N-glycosylation protocol requires only a catalytic amount of TMSOTf as promoter and proceeds smoothly at room temperature. (c) 2008 Elsevier Ltd. All rights reserved.

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