☆ 4.4 Article

Facile synthesis of α-iodo carbonyl compounds and α-iodo dimethyl ketals using molecular iodine and trimethylorthoformate

TETRAHEDRON LETTERS (2008)

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TETRAHEDRON LETTERS
Volume 49, Issue 23, Pages 3810-3813

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.03.151

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Categories

Chemistry, Organic

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A novel and direct method for the synthesis of alpha-iodo ketones and alpha-iodo dimethyl ketals from acetophenones using iodine and trimethylorthoformate under neutral conditions is described herein. (C) 2008 Elsevier Ltd. All rights reserved.

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