4.4 Article

The first approach to optically active 2,2′-bipyridine alkyl sulfoxides

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 4, Pages 719-722

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.11.104

Keywords

chiral 2,2 '-bipyridine alkyl sulfoxides; 5,5 '-bi-1,2,4-triazine; Diels-Alder reaction

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The synthesis of 6,6 '-bis(alkylsulfanyl)-2,2 '-bipyridines and their asymmetric oxidation to non-racemic 2,2'-bipyridine alkyl sulfoxides using either (+)-(8,8-dichlorocamphorylsulfonyl)oxaziridine or a modified Sharpless reagent is reported. (c) 2007 Elsevier Ltd. All rights reserved.

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