4.4 Article

Synthesis of oxindole-3-acetates through iron-catalyzed oxidative arylalkoxycarbonylation of activated alkenes

Journal

TETRAHEDRON
Volume 70, Issue 21, Pages 3466-3470

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2014.03.062

Keywords

Carbazates; Alkene difunctionalization; Alkoxycarbonylation/cyclization

Funding

  1. National Program on Key Basic Research Project of China (973 Program) [2013CB328900]
  2. National Natural Science Foundation of China [21202107, 21321061, J1310008, J1103315]

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An iron-catalyzed alkoxycarbonylation/cyclization reaction of N-arylacrylamides with carbazates has been developed. This new alkene difunctionalization reaction provides an efficient and straightforward method to obtain various ester-containing oxindoles. (C) 2014 Elsevier Ltd. All rights reserved.

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