Journal
TETRAHEDRON
Volume 69, Issue 41, Pages 8769-8776Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.07.100
Keywords
1,1-Dichloride; Aldehydes; Catalysis; Phosphine oxides
Categories
Funding
- EPSRC [EP/J000868/1]
- University of Nottingham
- EPSRC [EP/J000868/1, EP/H018034/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/J000868/1, EP/H018034/1] Funding Source: researchfish
Ask authors/readers for more resources
A phosphine oxide-catalyzed conversion of aldehydes into 1,1-dichlorides is reported. The reaction proceeds via a phosphorus(V)-catalysis manifold in which phosphine oxide turnover is achieved using oxalyl chloride as a consumable reagent. The new method is applicable to a range of aldehydes and, in combination with palladium-catalyzed reductive dimerization, gives rise to a new catalytic approach to the synthesis of stilbenes and a short formal synthesis of resveratrol. (C) 2013 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available