Journal
TETRAHEDRON
Volume 69, Issue 31, Pages 6461-6467Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.05.071
Keywords
Azoquinazolinones; Copper-catalyzed; Cascade reaction; C-N coupling; C-H Amination
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Funding
- Natural Science Foundation of Zhejiang [Y4110491]
- Natural Science Foundation of China [21072168, 21272169]
- Opening Foundation of Zhejiang Provincial Top Key Discipline [100061200102]
- Taizhou Science & Technology Program [111ZD02]
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A 'one-pot' method has been developed for the synthesis of azoquinazolinones from substituted 2-halobenzamides and different N-heterocycles via Cu(I)-catalyzed C-N coupling/C-H activation/C-N formation process under O-2. A number of azoquinazolinones containing different azole rings and substituents were obtained in good yields. (C) 2013 Elsevier Ltd. All rights reserved.
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