Journal
TETRAHEDRON
Volume 69, Issue 35, Pages 7258-7263Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.06.078
Keywords
Amidation; Cinnamamide; N-Substituted formamide; Ligand-free; Cinnamic acid
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Funding
- International S&T Cooperation Program of Jiangsu Province [BZ2010048]
- Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Key Laboratory of Organic Synthesis of Jiangsu Province
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A highly effective synthesis of alpha,beta-unsaturated acylamides is reported for the first time via copper-catalyzed direct amidation between readily available cinnamic acids and N-substituted formamides. The protocol was easily accessible and practical. (C) 2013 Elsevier Ltd. All rights reserved.
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