4.4 Article

A microwave assisted synthesis of benzoxazoles from carboxylic acids

Journal

TETRAHEDRON
Volume 69, Issue 2, Pages 791-795

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.10.084

Keywords

Benzoxazoles; Carboxylic acids; Amino acids; Cyanuric chloride; Microwave

Funding

  1. university of Sassari
  2. MIUR (Rome) within the project PRIN

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A series of various poly-substituted benzoxazoles were synthesized starting from readily available carboxylic acids. The method is based on TCT (cyanuric chloride)/microwave acid activation and it is characterized by mild conditions, allowing for a wide range of starting materials and functionalization of final products. (c) 2012 Elsevier Ltd. All rights reserved.

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