Journal
TETRAHEDRON
Volume 68, Issue 38, Pages 7827-7833Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.07.034
Keywords
Fe3O4/SiO2 nanoparticles; Nanomagnetic catalyst; Multicomponent reaction; One-pot; Diazepines
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Funding
- Iran National Science Foundation (INSF)
- Research Council of the Iran University of Science and Technology (IUST)
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In this research, a new protocol for the one-pot multicomponent synthesis of diazepine derivatives using a 1,2-diamine, a linear or cyclic ketone, and an isocyanide in the presence of a catalytic amount of silica-supported iron oxide (Fe3O4/SiO2) nanoparticles at ambient temperature in excellent yields is described. (c) 2012 Elsevier Ltd. All rights reserved.
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