Journal
TETRAHEDRON
Volume 68, Issue 2, Pages 754-760Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.10.068
Keywords
Marine natural product; Long linear polyacetylenes; Sponge; Antimicrobial
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Funding
- PRIN-MIUR
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Nine linear polyoxygenated acetylenes, fulvynes A-I (1-9), exhibiting the uncommon 2-yne carboxylic acid functionality, have been isolated from the butanolic extract of the Mediterranean sponge Haliclona fulva. Their structures possess a long alkyl chain with several oxygenated carbons, and were established by detailed spectroscopic analysis. All fulvynes were found to be active against a chloramphenicol-resistant strain of Bacillus subtilis. (C) 2011 Elsevier Ltd. All rights reserved.
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