Journal
TETRAHEDRON
Volume 68, Issue 40, Pages 8472-8479Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.07.073
Keywords
Spirooxindole; Isatin; 1,4-Dihydropyridines
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Funding
- Research Council of the University of Isfahan
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A one-pot, three-component condensation reaction of an isatin, isoxazole, and barbituric acid in water to give spirooxindoles in high yields, at 70 degrees C temperature, using a catalytic amount of p-toluene sulfonic acid, is described. (C) 2012 Elsevier Ltd. All rights reserved.
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