Journal
TETRAHEDRON
Volume 68, Issue 1, Pages 250-261Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.10.053
Keywords
12-Oxobenzo[c]phenanthridinone; 4-Substituted 3-arylisoquinolone; Vilsmeier-Haack reaction; Mitsunobu reaction; Knoevenagel condensation
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Funding
- Korea Research Foundation [NRF-2011-0015551]
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Vilsmeier-Haack reaction on 3-arylisoquinolones resulted in versatile 4-formylated 3-arylisoquinolones that were further derivatized into 12-oxobenzo[c]phenanthridinones, 4-alkoxymethyl-3-arylisoquinolones, 3aryl-4-phenoxymethylisoquinolones, 4-aminomethyl-3-arylisquinolone, and 3-isoquinolinyl-2-phenyl-acrylonitrile by different synthetic strategies. (C) 2011 Elsevier Ltd. All rights reserved.
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