Journal
TETRAHEDRON
Volume 68, Issue 37, Pages 7663-7669Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.05.086
Keywords
Diynylation; Propargylamines; Addition; Enantioselectivity; Ketimines
Categories
Funding
- NSFC [20902067, 20972110]
- Ministry of Education of China
Ask authors/readers for more resources
A facile and effective enantioselective addition of terminal 1,3-diynes to acyclic alpha-CF3 ketimine esters has been developed by using zinc/Binol complexes. The reaction works well with a variety of aromatic-, aliphatic- and silyl-substituted diynes, providing the desired products in up to 97% yield and 97% enantiomeric excess. (C) 2012 Published by Elsevier Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
