4.4 Article

Reactivity of sugar α-aminonitrile derivatives under titanium-mediated cyclopropanation conditions

Journal

TETRAHEDRON
Volume 68, Issue 4, Pages 1145-1152

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.11.067

Keywords

Nitriles; Cyclopropylamine; Titanium-catalyzed cyclopropanation; Imidazoline

Funding

  1. Conseil Regional de Picardie

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The reactivity of different sugar alpha-aminonitriles has been studied under titanium-mediated cyclo-propanation conditions. This study has been performed on amide, lactam, and imide derivatives. It has been possible to obtain spiro[furanose-3,3'-(3',5',6',7'-tetrahydrospiro[cyclopropane-1,2'-pyrrolo[1,2-a] imidazole])] derivatives. (C) 2011 Elsevier Ltd. All rights reserved.

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