Journal
TETRAHEDRON
Volume 67, Issue 12, Pages 2220-2231Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.01.082
Keywords
Ligularia lamarum; Ligularia subspicata; Furanoeremophilane; Sesquiterpenoid; atpB-rbcL; ITS
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Funding
- JSPS [21404009]
- Grants-in-Aid for Scientific Research [21404009] Funding Source: KAKEN
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Root chemicals and DNA sequences were analyzed for Ligularia lamarum samples collected in Yunnan and Sichuan Provinces of China and the relationship between the plant and Ligularia subspicata, its taxonomically closest species, was examined. Both species produce furanoeremophilanes and eremophilan-8-one derivatives as the major components. Eleven new compounds, including a new seco-bakkane compound, were isolated. The two species were found to harbor overlapping intra-specific diversities with respect to the chemicals and the DNA sequences. (C) 2011 Elsevier Ltd. All rights reserved.
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