Journal
TETRAHEDRON
Volume 67, Issue 25, Pages 4530-4534Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.04.085
Keywords
Acetylene; Sponge; Cytototoxic; Structure elucidation
Categories
Ask authors/readers for more resources
Cytototoxic linear acetylenes, miyakosynes A-F, were isolated from a marine sponge Petrosia sp. Their structures were elucidated by a combination of spectroscopic analyses and chemical methods. The absolute configuration of the secondary alcohols at each terminus was determined by the modified Mosher's analysis. Miyakosynes show cytotoxicity against HeLa cells at submicromolar concentrations. (C) 2011 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available