4.4 Article

A total synthesis of (±)-α-cyclopiazonic acid using a cationic cascade as a key step

Journal

TETRAHEDRON
Volume 67, Issue 44, Pages 8515-8528

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.08.094

Keywords

alpha-Cyclopiazonic acid; Synthesis; Carbenium ion; Cascade; Indole alkaloid

Funding

  1. EPSRC

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The indole alkaloid alpha-cyclopiazonic acid 1 has been synthesised by a route, which features at its core an acid-catalysed cationic cascade cyclisation terminated by a sulfonamide group. (C) 2011 Elsevier Ltd. All rights reserved.

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