4.4 Article

An 'off-on' fluorescent chemosensor of selectivity to Cr3+ and its application to MCF-7 cells

Journal

TETRAHEDRON
Volume 67, Issue 37, Pages 7096-7100

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.07.008

Keywords

Fluorescence; Chemosensor; Metal ion recognition; Cr3+-selective sensor; Imaging agents

Funding

  1. NSFC [50903075, 60978034, 50873093]

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A 'switching-on' fluorescent chemosensor for the selective and sensitive signaling of intraceullar Cr3+ has been designed and synthesized exploiting the guest-induced prohibition of the photoinduced electron transfer process between naphthyridine moiety and 7,10-diphenylfluoranthene moiety, the system shows a Cr3+-selective chelation-enhanced fluorescence response not only in ethanol but in cell. (C) 2011 Elsevier Ltd. All rights reserved.

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