4.4 Article

A selenolactone-based fluorescent chemodosimeter to monitor mecury/methylmercury species in vitro and in vivo

Journal

TETRAHEDRON
Volume 66, Issue 23, Pages 4016-4021

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.04.042

Keywords

Fluorescent chemodosimeter; Selenolactone; Rhodamine; Mecury; Methylmercury

Funding

  1. Korea Research Foundation [KRF-2006-005-J04002]
  2. National Research Foundation of Korea (NRF) [20090083065]
  3. National Creative Research Initiative
  4. WCU [R32-2008-000-10217-0]
  5. National Research Foundation of Korea [2006-005-J04002] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A fluorescent probe based on selenolactone displays unique fluorescence enhancement and UV vis spectral change for mercury/methylmercury species, which were attributed to deselenation reaction. The value of this system was successfully demonstrated by its use in detecting inorganic mercury/methylmercury species in cells and zebrafish. (C) 2010 Elsevier Ltd. All rights reserved.

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