Journal
TETRAHEDRON
Volume 66, Issue 14, Pages 2598-2601Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.02.038
Keywords
One-pot synthesis; Stereoselectivity; Spirocyclopropyl oxindoles; Isatins; Arsonium ylides
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Funding
- National Natural Science Foundation of China [20872088]
- Shanghai Municipal Education Commission [J50102]
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A one-pot approach for highly stereoselective synthesis of spirocyclopropyl oxindoles 3 with good to excellent yields from the reaction of isatins 1 and arsonium salts 2 in the presence of K(2)CO(3) is described The structure of product 3 was confirmed by (1)H NMR, (13)C NMR, IR, MS, EA, and X-ray diffraction as well (C) 2010 Elsevier Ltd All rights reserved
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