4.4 Article

A synthetic approach to carbazoles using electrochemically generated hypervalent iodine oxidant

Journal

TETRAHEDRON
Volume 66, Issue 52, Pages 9779-9784

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.11.015

Keywords

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Funding

  1. Scientific Research C, High-Tech Research Center Project for Private Universities
  2. MEXT

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Carbazoles were successfully synthesized by oxidative cyclization of the corresponding diaryl derivatives using electrochemically generated hypervalent iodine oxidant. Electron-withdrawing nitro and donating methoxy groups at the para position of the acetamide group interfered with cyclization. Glycozoline (8) was successfully synthesized in five steps with 50% overall yield. (C) 2010 Elsevier Ltd. All rights reserved.

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