Journal
TETRAHEDRON
Volume 66, Issue 6, Pages 1280-1288Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.12.020
Keywords
Meridianins; Indoles; Alkynes; Nitrosoarenes; Kinase inhibitors
Categories
Funding
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [848591] Funding Source: National Science Foundation
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Meridianins, marine alkaloids known as kinase Inhibitors with an indole skeleton, and meridianin analogues were produced regioselectivity and in moderate to good yields by thermal annulation of nitrosoarenes with 2-amino-4-ethynylpyrimidine and 2-chloro-4-ethynylpyrimidine, respectively, through a novel and atom-economical indolization process (C) 2009 Elsevier Ltd All rights reserved
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