Journal
TETRAHEDRON
Volume 66, Issue 27-28, Pages 5101-5106Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.04.111
Keywords
Deep ocean derived fungus; Sorbicillin trimer; Trisorbicillinone; Phialocephala sp
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Funding
- Chinese Ocean Mineral Resource R D Association [DY105-2-04]
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Eighteen sorbicillonoids, including three new sorbicillin trimers, trisorbicillinones B (2), C (3), and D (4), were isolated from a deep ocean sediment derived fungus, Phialocephala sp. FL30r. Their structures were determined by IR. MS, CD, and NMR spectral data. The cytotoxic activities of the new trisorbicillinones B (2), C (3), and D (4) were tested against both P388 and K562 cell lines. (C) 2010 Elsevier Ltd. All rights reserved.
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