Journal
TETRAHEDRON
Volume 66, Issue 26, Pages 4841-4853Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.04.016
Keywords
Enantiopure isoxazolidinone monomers; beta(3)-oligopeptides; Amide ligation
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Funding
- Arnold and Mabel Beckman Foundation
- David and Lucille Packard Foundation
- Research Corporation
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The design and general synthesis of enantiopure isoxazolidinone monomers as precursors for the preparation of enantiopure N-terminal hydroxylamine-beta(3)-oligopeptides, which may be used as reaction partners with alpha-ketoacids in the decarboxylative amide ligation reaction, is described. (C) 2010 Elsevier Ltd. All rights reserved.
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