4.4 Article

A facile synthesis of chromeno[3,4-c]spiropyrrolidine-oxindoles via 1,3-dipolar cycloadditions

Journal

TETRAHEDRON
Volume 66, Issue 34, Pages 6744-6748

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.06.078

Keywords

Azomethine ylide; 1,3-Dipolar cycloaddition; Chromeno[3,4-c]spiropyrrolidine-oxindole

Funding

  1. University of Tehran

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A facile one-pot synthesis of chromene bearing novel spiropyrrolidine-oxindoles has been accomplished by the [3+2]-cycloaddition reaction of 3-acetyl-2H-chromen-2-ones with azomethine ylides derived in situ from isatin or N-methyl isatin with sarcosine. (C) 2010 Elsevier Ltd. All rights reserved.

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