Journal
TETRAHEDRON
Volume 66, Issue 6, Pages 1236-1243Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.12.028
Keywords
Oxidation of indole; Mannich-type reaction; 2,2-Disubstituted 1,2-dihydro-3H-indol-3-one; C-Acyliminium intermediate
Categories
Funding
- Ministry of Education, Science, Sports and Cultur [21790027]
- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [S0801043]
- Grants-in-Aid for Scientific Research [21590028] Funding Source: KAKEN
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A novel preparative method for 2.2-disubstituted 1,2-dihydro-3H-indol-3-ones through the oxidation of 2-arylindoles followed by a Mannich-type reaction with carbon nucleophiles is described (C) 2009 Elsevier Ltd All rights reserved
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