Journal
TETRAHEDRON
Volume 66, Issue 40, Pages 7995-7999Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.08.016
Keywords
Primary alkylamine; Alkyl isocyanide; Acetylenic ester; 1,2-Dihydropyridine; MCRs; Cascade reaction
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A novel one-pot isocyanide-based cascade four-component reaction between primary alkylamines, acetylenic esters, and alkyl isocyanides led to tetraalkyl 1-alkyl(aryl)-4-alkylamino-1,2-dihydropyridine-2,35,6-tetracarbxylates in good yields. (C) 2010 Elsevier Ltd. All rights reserved.
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