Journal
TETRAHEDRON
Volume 66, Issue 47, Pages 9252-9262Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.09.042
Keywords
Cross coupling; Oxindoles; Reductive cyclization; Ullmann reaction
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Funding
- Institute of Advanced Studies
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The Pd[0]-catalyzed Ullmann cross-coupling of o-nitrohaloarenes 1a-e with the brominated heterocycles 2a-f delivers the expected products 3a-j in good to excellent yields The reductive cyclization of such products as well as N-acyl derivatives 3k I and m has been investigated and provided the C-3 mono-substituted oxindoles 5a-d f g k and m the direct reduction products 41 and J or indole 51 (C) 2010 Elsevier Ltd All rights reserved
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