4.4 Article

Metabolites from the endophytic fungi Botryosphaeria rhodina PSU-M35 and PSU-M114

Journal

TETRAHEDRON
Volume 65, Issue 51, Pages 10590-10595

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.10.084

Keywords

Botryosphaeria rhodina; Dimeric gamma-lactone; Hexahydroindenofuran; Antibacterial activity

Funding

  1. Commission on Higher Education
  2. TRF Senior Research Scholar [RTA5180007]
  3. Center for Innovation in Chemistry (PERCH-CIC)
  4. Graduate School, Prince of Songkla University

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Three dimeric gamma-lactones (1-3), one dihydronaphthalene-2,6-dione (4), one hexahydroindenofuran (5), one cyclopentanone (6), and one lasiodiplodin (7) were isolated from the endophytic fungi Botryosphaeria rhodina PSU-M35 and PSU-MT114 along with twelve known metabolites. The structures and the proposed stereochemistry of the new metabolites were established by spectral data analysis. The isolated compounds were submitted for evaluation of the antibacterial activity against Staphylococcus aureus, both standard and methicillin-resistant strains. (C) 2009 Elsevier Ltd. All rights reserved.

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