Journal
TETRAHEDRON
Volume 65, Issue 16, Pages 3261-3269Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.10.048
Keywords
Sigmatropic rearrangements; Sceletium alkaloids; Mesembrine; Joubertinamine
Categories
Ask authors/readers for more resources
Joubertinamine and mesembrine are two related alkaloids isolated from Sceletium plants. From the perspective of chemical synthesis, the major challenge posed by joubertinamine and mesembrine is Undoubtedly the construction of the benzylic quaternary stereogenic center. We became intrigued by the prospect of applying Successive sigmatropic rearrangements to build the key structural features of these alkaloids in enantioselective manner. In this article, We detail Our results in this area, which include the enantioselective total synthesis Of (-)-joubertinamine and (-)-mesembrine. (C) 2008 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available