Journal
TETRAHEDRON
Volume 65, Issue 15, Pages 2982-2988Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.01.104
Keywords
Substituted 4-amino-1,3-thiazoles; Substituted 4-amino-1,3-selenazoles; Dimethyl cyanodithioimidocarbonate
Categories
Funding
- Ministere de l'Education Nationale, de l'Enseignement Superieur et de la Recherche
- Universite du Luxembourg
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In this work, we describe the synthesis of new 2,4,5-trisubstituted-1,3-thiazoles and 1,3-selenazole achieved by an easy one-pot four-step procedure. Expected compounds were obtained in good yield from dimethyl cyanodithioimidocarbonate, which was the common starting material for the preparation of all 1,3-thiazoles and 1,3-selenazoles, Chemical diversity was introduced on thiazole and selenazole rings by varying the amines and the activated halides used. (C) 2009 Elsevier Ltd. All rights reserved.
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