Journal
TETRAHEDRON
Volume 65, Issue 47, Pages 9797-9800Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.09.076
Keywords
One-pot; Aryl alpha-keto esters; Selenium dioxide; Ketalization
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Funding
- National Natural Science Foundation of China
- Nippon Chemical Industrial Co., Ltd
- Shanghai Jjiao Tong University
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A novel one-pot synthesis of aryl alpha-keto esters was developed through oxidation of aryl-ketones using selenium dioxide, esterification accompanied by ketalization, and hydrolysis. Both aromatics and heteroaromatics gave good yields by this one-pot method. (C) 2009 Elsevier Ltd. All rights reserved.
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