Journal
TETRAHEDRON
Volume 65, Issue 27, Pages 5427-5437Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.04.032
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Funding
- Ministere de la Recherche et de l'Enseignement Superieur
- European Union [LSHB-CT-2004-503467]
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The synthesis of 2-, 3-, 4-, and 6-substituted pyrido[2,3-b]indoles (alpha-carbolines) by palladium-catalyzed cross-coupling reactions from the corresponding halopyrido[2,3-b]indoles is described. A sequential and a one-pot chemoselective double Suzuki-Miyaura coupling route is presented for the synthesis of symmetrically and unsymmetrically disubstituted pyrido[2,3-b]indoles. (C) 2009 Elsevier Ltd. All rights reserved.
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