Journal
TETRAHEDRON
Volume 65, Issue 40, Pages 8434-8439Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.07.050
Keywords
Benzotriazole; Dihalobenzene; Cul; Indole; N-arylation
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Funding
- Department of Science and Technology (DST), Govt. of India
- National Institute of General Medicine [GM 070620, GM 079593]
- Ministry of Science and Technology, Govt. of India
- CSIR, India
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A general, efficient, and inexpensive method for the N-arylation of indoles using a catalytic system derived from Cul and benzotriazole is reported. Selective mono N-arylation of indoles with ortho-di-haloarenes has also been successfully achieved in good yields using this protocol. (C) 2009 Published by Elsevier Ltd.
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