4.4 Article

Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Journal

TETRAHEDRON
Volume 65, Issue 1, Pages 51-56

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.10.076

Keywords

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Funding

  1. MUR (PRIN 2007) Sostanze Naturali ed Analoghi Sintetici con Attivita Antitumorale Rome, Italy

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Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here. (C) 2008 Elsevier Ltd. All rights reserved.

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