4.4 Article

Copper-catalysed intramolecular O-H addition to unactivated alkenes

Journal

TETRAHEDRON
Volume 65, Issue 50, Pages 10334-10338

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.10.055

Keywords

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Funding

  1. Fundacion Caixa Galicia
  2. Xunta Galicia (Angeles Alvarino)
  3. Ministerio de Educacion y Ciencia [CTQ2006-15621-C02-01/BQU]
  4. EPSRC/GSK

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Intramolecular cyclisation of omega-alkenoic acids and alkenols can be achieved using a catalytic amount of Cu(OTf)(2) to afford lactones and cyclic ethers, offering a practical alternative to existing catalysts. (C) 2009 Elsevier Ltd. All rights reserved.

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