4.4 Article

Copper(I)-2-(2′-pyridyl)benzimidazole catalyzed N-arylation of indoles

Journal

TETRAHEDRON
Volume 65, Issue 50, Pages 10459-10462

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.10.014

Keywords

N-arylation; Nitrogen ligand; Bidentate ligand; Benzimidazole

Funding

  1. Ministry of Education, Culture, Sports, Science and Technology, Japan [B17340020]

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Cul-2-(2'-pyridyl)benzimidazole catalyst system can serve efficiently to promote N-arylation of various indoles to afford the N-arylated indoles. The bidentate ligand, 2-(2'-pyridyl)benzimidazole was proved superior to monodentate nitrogen-based ligands and well-known bidentate ligands such as 2,2'-bipyridyl and 1,10-phenanthroline. (C) 2009 Published by Elsevier Ltd.

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