4.4 Article

Synthesis and photophysical properties of novel cyclonucleosides - substituent effects on fluorescence emission

Journal

TETRAHEDRON
Volume 64, Issue 30-31, Pages 7151-7158

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.05.098

Keywords

fluorescent nucleosides; cyclonucleosides; Sonogashira; cycloaddition

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An intramolecular [3+2]-cycloaddition between an azide and a disubstituted alkyne afforded a number of novel adenosine-derived cyclonucleosides, which exhibited fluorescence in the visible range. The synthesis and photophysical properties of these potential fluorescent probes are described. (c) 2008 Elsevier Ltd. All rights reserved.

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