Journal
TETRAHEDRON
Volume 64, Issue 19, Pages 4162-4173Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.03.001
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The enantioselective synthesis of benzo-annulated oxa-heterocycles 2,3-dihydrobenzofuran and 1-benzopyran derivatives is described using beta-hydroxy-alpha-tosyloxy esters as chiral building blocks, which are easily accessible through the regioselective alpha-tosylation of Sharpless asymmetric dihydroxylation-derived syn-2,3-dihydroxy esters. (c) 2008 Elsevier Ltd. All rights reserved.
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