4.4 Article

An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

Journal

TETRAHEDRON
Volume 64, Issue 37, Pages 8938-8942

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.06.057

Keywords

quinones; multicomponent reactions; Knoevenagel heteroDiels-Alderreactions; MW irradiation

Funding

  1. Spanish MCYT [SAF2006-06720]
  2. ICIC

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The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero, Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used. (C) 2008 Published by Elsevier Ltd.

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