4.4 Article

Click chemistry as an efficient tool to access β-cyclodextrin dimers

Journal

TETRAHEDRON
Volume 64, Issue 30-31, Pages 7159-7163

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.05.095

Keywords

click chemistry; cycloaddition; cyclodextrin; dimers; supramolecular chemistry

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The Cu(I)-catalyzed azide-alkyne cycloaddition has enabled practical and efficient preparation of hydroxylated, permethylated and peracylated beta-cyclodextrin dimers in good yields starting from mono-6-azido-beta-cyclodextrin and ortho-, meta- or para-bis-(prop-2-ynyloxy)benzenes as spacers. (c) 2008 Elsevier Ltd. All rights reserved.

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