Journal
TETRAHEDRON
Volume 64, Issue 44, Pages 10148-10154Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2008.08.047
Keywords
Solvent-free; Ball-milling; Propargylic alcohol; Naphthopyran
Categories
Funding
- National Natural Science Foundation of China [20621061, 20772117]
- National Basic Research Program of China [2006CB922003]
- Anhui Provincial Bureau of Education [ZD2007005-1]
Ask authors/readers for more resources
Under solvent-free ball-milling conditions, the nucleophilic addition reactions of terminal alkynes to carbonyl compounds promoted by KOH proceeded efficiently at ambient temperature. Subsequent cyclization reactions of the synthesized propargylic alcohols with 2-naphthol catalyzed by indium trichloride tetrahydrate, leading to the formation of naphthopyrans, were then investigated. In most cases, side reactions were avoided and thus high yields were achieved. (c) 2008 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available