Journal
TALANTA
Volume 125, Issue -, Pages 313-318Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2014.03.020
Keywords
Molecular modelling; MIP; Solid phase extraction (SPE); Selective extraction; Olive oil; Fenthion
Categories
Funding
- Association biocapteurs-materiaux a empreinte moleculaire pour la detection des insecticides utilises sur l'olivier [MA/09/215]
Ask authors/readers for more resources
A combination of molecular modelling and a screening of the library of non-imprinted polymers (NIPs) was used to identify acrylamide as a functional monomer with high affinity towards fenthion, organophosphate insecticide, which is frequently used in the treatment of olives. A good correlation was found between the screening tests and modelling of monomer-template interactions performed using a computational approach. Acrylamide-based molecularly imprinted polymer (MIP) and non-imprinted polymer (NIP) were thermally synthesised in dimethyl formamide (porogen) using ethylene glycol dimethacrylate as a cross-linker and 1,1-azo-bis (isobutyronitrile) as an initiator. The chemical and physical properties of the prepared polymers were characterised. The binding of fenthion by the polymers was studied using solvents with different polarities. The developed MIP showed a high selectivity towards fenthion, compared to other organophosphates (dimethoate, methidathion malalthion), and allowed extraction of fenthion from olive oil samples with a recovery rate of about 96%. The extraction of fenthion using MIPs was much more effective than traditional C-18 reverse-phase solid phase extraction and allowed to achieve a low detection limit (LOD) (5 mu g L-1). (C) 2014 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available