Journal
SYNTHETIC COMMUNICATIONS
Volume 44, Issue 9, Pages 1173-1211Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2012.760129
Keywords
solvent-free synthesis; solid-phase synthesis; Heterocycles
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Solid-phase organic synthesis is a rapidly expanding area of synthetic chemistry that is being widely exploited in the search for new medicinally important compounds using combinatorial techniques. In recent decades, a large number of reports related to solid-phase synthesis of heterocycles have appeared because of the wide variety of their biological activity. In this review, we report the important role of solid-phase synthesis in the synthesis of nitrogen containing six-membered ring heterocycles.
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